Nanotechnology in Medicine and Biology

Major: Biomedical Engineering (Internet of Things)
Code of subject: 6.163.03.E.86
Credits: 5.50
Department: Electronics and Information Technology
Lecturer: Professor Dmytro Zayachuk
Semester: 8 семестр
Mode of study: денна
Learning outcomes: Having mastered the discipline, the student must be able to demonstrate the following learning outcomes: • To understand and deeply know the basics and physical principles of modern nanotechnology in application to the needs of medicine and biology. • To know the possibilities of visualization and observation of nanostructures of biological and medical objects and be able to choose the optimal ones to solve specific problems. • To understand the essence of nanomedicine, its main goals and potential ways to achieve these goals. • To have in-depth knowledge of the problem of targeted drug delivery as a medical nanotechnology and method of treatment, its purpose, delivery systems and requirements for them, means of addressing systems and their guidance on the affected tissues and organs. • To understand the possibility of using materials of organic origin, in particular, liposomes and dendrimers, for the nanomedicine needs. • To understand the possibility of using carbon-based materials, in particular, fullerenes and carbon nanotubes, for nanomedicine needs. • To understand on the possibility of using metal nanostructures and semiconductor quantum dots for the nanomedicine needs. • To have a substantive notion the application of nanotechnology and nanomaterials in various fields of medicine.
Required prior and related subjects: Pre-requisites: Absent Co-requisites: Absent
Summary of the subject: The basics of nanotechnology in their application to the needs of medicine and biology are taught: basic concepts of nanomedicine; visualization of nanoobjects of biological origin; targeted drug delivery and system of its implementation; issues of nanocarriers for drug transport, means of their addressing and targeting; modern materials for nanomedicine: liposomes, dendrimers, nanostructures of carbon fullerenes and nanotubes, metal nanoshells and nanoparticles, semiconductor quantum dots; application of nanotechnologies and nanomaterials in various fields of medicine: oncology, cardiology, endocrinology, traumatology, orthopedics, ophthalmology, dentistry; potential risks that the use of nanotechnology in medicine may create.
Assessment methods and criteria: Current control: Presentations at practical classes, solving tasks Final control: Exam (written and oral components) The distribution of points according to a 100-point scale Current control – 25 points Exam control – 75 points Of which: Written component – 50 points Oral component – 25 points
Recommended books: 1. Заячук Д.М., Нанотехнології і наноструктури, Львів, 2009. 2. Волков С. В., Ковальчук С. П., Генко В. М., Решетняк О. В.– Нанохімія. Наносистеми. Наноматеріали / К.: Наукова думка, 2008.– 422 с. 3. І.С. Чекман , 3.Р. Ульберг , В.О. Маланчук, Н.О. Горчакова , І. А . Зупанець, Нанонаука, нанобіологія, нанофармація. Монографія - К.:Поліграф плюс , 2012. - 328 с . 4. Дыкман Л. А., Богатырев В. А., Щеглов С. Ю., Хлебцов Н. Г.Золотые наночастицы: синтез, свойства, биомедицинское применение /– М.: Наука, 2008.– 319 с. 5. С. М. Шульга, Ліпосоми і наносоми: структура, властивості, виробництво, Огляд, BIOTECHNOLOGIA ACTA, 2013, V. 6, No 5, с. 19-40. 6. Л.И. Барсуков, Липосомы, Соросовский обозревательный журнал, 1998, №10, с. 2-9. 7. Ю.Д. Семчиков, Дендримеры – новый класс полимеров, Соросовский обозревательный журнал, 1998, №12, с. 45-51. 8. Yu-Chen Wang, Eric Rheaume, Frederic Lesage, and Ashok Kakkar, Synthetic Methodologies to Gold Nanoshells: An Overview, Review, Molecules 2018, 23, 2851; doi:10.3390/molecules23112851 9. Christopher Loo, Alex Lin, Leon Hirsch, Min-Ho Lee, Jennifer Barton, Naomi Halas, JenniferWest, Rebekah Drezek, Nanoshell-Enabled Photonics-Based Imaging and Therapy of Cancer, Technology in Cancer Research & Treatment, 2004, Volume 3, Number 1, pages 33-40.